CYCLE NITISINONE TABLETS F.A.Q.

NITISINONE TABLETS are used for the treatment of hereditary tyrosinemia type 1 (HT-1), in addition to limiting the amount of tyrosine and phenylalanine in the diet.
NITISINONE TABLETS stop the build-up of toxic substances which cause the severe liver and kidney problems in patients with HT-1. By doing that, they also prevent the porphyric crises associated with HT-1.
Medicinal ingredients: Nitisinone. Non-medicinal ingredients: Glyceryl dibehenate, Lactose mono hydrate. Do not use NITISINONE if you are allergic to Nitisinone or other ingredients of this medicine.
NITISINONE TABLETS are usually taken twice a day. Swallow the tablets whole with a drink of water. NITISINONE TABLETS can be taken with or without food. For infants, NITISINONE TABLETS may be crushed between two spoons and mixed with 5 mL of water before being given using a syringe. The crushed tablets are not to be given using a baby bottle. Crushed tablets may also be mixed with semi-soft food such as apple sauce. Your healthcare professional will tell you if you can crush NITISINONE TABLETS and how many tablets you should crush. Crushing NITISINONE TABLETS can lower the amount of drug you receive. Your healthcare professional may need to adjust your dose after blood tests have been done to see how you are responding to treatment.
Your healthcare professional will tell you how many NITISINONE TABLETS to take and when to take them.
If you think you have taken too many NITISINONE TABLETS, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms. If you go to a healthcare professional or to the hospital, take the NITISINONE TABLETS container with you.
If you forget a dose, take the next dose as planned. Do not take a double dose to make up for a forgotten dose. If you forget to take a dose, contact your healthcare professional or pharmacist.
These are not all the possible side effects you may feel when taking NITISINONE TABLETS. If you experience any side effects not listed here, contact your healthcare professional. NITISINONE TABLETS can cause abnormal blood test results. While you are taking NITISINONE TABLETS your healthcare professional will decide when to perform blood tests and will interpret the results. For more information please see product monograph.
Keep out of reach and sight of children. Store your tablets at room temperature (15 – 30°C), in a dry place. Keep the container tightly closed. There is an expiry date on the label. Do not use the medicine after this date.

INDICATION AND CLINICAL USE

Nitisinone Tablets are indicated for the treatment of hereditary tyrosinemia type 1 (HT-1) in combination with dietary restriction of tyrosine and phenylalanine.

Treatment with Nitisinone Tablets should be initiated and supervised by a physician experienced in the treatment of HT-1.

IMPORTANT INFORMATION ABOUT NITISINONE TABLETS

How do NITISINONE TABLETS work? NITISINONE TABLETS stop the build-up of toxic substances which cause the severe liver and kidney problems in patients with HT-1. By doing that, they also prevent the porphyric crises associated with HT-1.

What are the ingredients in NITISINONE TABLETS? 

  • Medicinal ingredients: Nitisinone
  • Non-medicinal ingredients: glyceryl dibehenate, lactose monohydrate.

Do not use NITISINONE TABLETS if you:

  • Are allergic (hypersensitive) to nitisinone or any of the other ingredients in NITISINONE TABLETS.
  • Are breast-feeding. Do not breast feed while taking NITISINONE TABLETS.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take NITISINONE TABLETS. Talk about any health conditions or problems you may have, including if you:

  • Are pregnant or planning to become pregnant.

How to take NITISINONE TABLETS

  • NITISINONE TABLETS are usually taken twice a day.
  • Swallow the tablets whole with a drink of water. NITISINONE TABLETS can be taken with or without food.
  • For more information on infant administration refer to the product monograph.

Overdose: If you think you have taken too many NITISINONE TABLETS, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms. If you go to a healthcare professional or to the hospital, take the NITISINONE TABLETS container with you.

Missed Dose: If you forget a dose, take the next dose as planned. Do not take a double dose to make up for a forgotten dose. If you forget to take a dose, contact your healthcare professional or pharmacist.

Storage:
Keep out of reach and sight of children. Store your tablets at room temperature (15 – 30°C), in a dry place. Keep the container tightly closed. There is an expiry date on the label. Do not use the medicine after this date.

PLEASE SEE PRODUCT MONOGRAPH
GO TO HOME PAGE